Neuromodulation of spinal circuits

Neuromodulators are chemical signals that are released by cells in the nervous system and fine tune properties of neural networks. This fine-tuning allows networks to generate a diverse array of outputs and is accomplished through altering the electrical properties of neurons and the connections (synapses) formed between them. In the context of movement control, this may give motor networks the capacity to ‘reconfigure’ and generate a wide range of movements.

My work focuses on two neuromodulatory systems with a primary focus on spinal locomotor circuits and a secondary focus on respiratory circuits:

Click on the images above to learn more about these neuromodulatory systems