
| SIMON A. SHARPLES, PHD Research Fellow Crone Lab Cincinnati Children’s Hospital |
I am a Canadian postdoctoral fellow in the lab of Dr. Steven Crone at Cincinnati Children’s Hospital, and have been supported by prestigious international fellowships from the Natural Sciences and Engineering Research Council of Canada (NSERC), the Canadian Institutes of Health Research (CIHR), and the Royal Society (Newton International Fellowship).
My goal is to pursue a career in academia, combining my passions for research, teaching, and mentorship. My research focuses on understanding the fundamental mechanisms that enable the nervous system to generate and adapt movement. Using a multidisciplinary toolkit in rodent models, I study spinal circuits that control locomotion and breathing. Through this work, I aim to uncover mechanisms that can inform novel therapeutic strategies for restoring breathing and motor function following neural injury and in neurological disorders.
I am currently seeking a tenure-track faculty position where I can establish an independent research program complemented by teaching motor systems physiology at both undergraduate and graduate levels.
Professional profiles
Recently Published Work
Intrinsic mechanisms contributing to the biophysical signature of mouse gamma motoneurons (Published in The Journal of Physiology)

A cholinergic spinal pathway for the adaptive control of breathing (Published in Cell Reports)
Outside of the lab
In addition to being the primary focus of my research, movement is also an integral part of my life. I am an avid angler and outdoor enthusiast. When I’m not in the lab you can find me doing my best to get lost!









